Air Fryer Roast Beef Sandwich

Section: Recipes Inspired by Your Favorite Restaurants

Experience a quick and easy way to enjoy tender roast beef layered with creamy Swiss cheese on toasted brioche buns. A special sauce made from mayonnaise, stone ground mustard, and prepared horseradish adds a flavorful kick to each bite. Using an air fryer, the sandwich gets perfectly warmed and toasted in just minutes, making it a perfect choice for a satisfying lunch or dinner. Optional sauce substitutions and cheese swaps allow for customization to suit all tastes.

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Crafted By Lana
Updated on Mon, 12 Jan 2026 01:16:14 GMT
A sandwich with meat and cheese on a wooden table. Pin it
A sandwich with meat and cheese on a wooden table. | lanatable.com

Air Fryer Roast Beef Sandwiches are a quick and satisfying way to enjoy a warm, cheesy meal any day of the week. Stuffed with tender roast beef, melted Swiss cheese, and a tangy sauce, these sandwiches deliver comforting flavors with minimal effort. Perfect when you want something hearty but easy to prepare, they come together in under twenty minutes and make for a great lunch or dinner option.

I first made these sandwiches on a hectic weeknight, and they quickly became a favorite because everyone loved the gooey cheese and savory roast beef. Now they are a go-to meal when I need something fast but delicious.

Ingredients

  • Mayonnaise: provides creaminess and moisture— best to use full-fat for richness
  • Stone ground mustard: adds a gentle pungent tang and texture— look for brands with visible mustard seeds for authenticity
  • Prepared horseradish: gives a spicy kick— adjust amount to your spice tolerance or omit if preferred
  • Brioche buns: soft with slight sweetness, perfect for toasting and holding the fillings— fresh buns toast best for that perfect crunch
  • Swiss cheese: melts beautifully and has a nutty flavor— Havarti or provolone work well as substitutes for different tastes
  • Thinly sliced deli roast beef: tender and flavorful, the star protein— leftover roast beef also works great here

Instructions

Saucemaker:
Mix together the mayonnaise, stone ground mustard, and prepared horseradish thoroughly in a small bowl. This sauce adds a creamy tang that complements the beef perfectly.
Prepare the Air Fryer:
Optional but helpful You can line your air fryer basket with aluminum foil for easier cleanup. Place two bottom buns and two top buns directly in the basket and spread a generous layer of the sauce on each bun side.
Layer the Sandwich:
Put one slice of Swiss cheese on each bun piece. On each bottom bun, layer about five slices of roast beef evenly over the cheese.
Air Fry the Sandwiches:
Set your air fryer to 370 degrees Fahrenheit and cook the sandwiches for 4 to 6 minutes. The goal is to warm the meat and melt the cheese while toasting the buns slightly. If the buns brown too quickly, you can remove the top halves after a few minutes and let the bottoms finish to avoid burning.
Finish and Serve:
Remove the sandwiches from the air fryer and assemble by placing the top buns over the beef and cheese. Serve immediately while warm and melty. Any leftover sauce can be offered on the side or saved for the next batch.
A sandwich with meat and cheese on top. Pin it
A sandwich with meat and cheese on top. | lanatable.com

Swiss cheese has always been my favorite here because it melts so well and adds a subtle nuttiness that pairs beautifully with roast beef. This sandwich reminds me of cozy family dinners where quick comfort food was key but still felt special.

Storage Tips

Store any leftover sandwiches in an airtight container in the refrigerator for two to three days. Keep in mind the buns may soften, so toasting them quickly before reheating helps bring back some crispness. Avoid freezing assembled sandwiches as the bread texture will degrade.

Ingredient Substitutions

If you do not have stone ground mustard try Dijon mustard for a smoother, slightly more vinegary flavor. Mayo can be swapped with plain Greek yogurt for a lighter sauce but this changes the creaminess. For cheese, havarti or provolone are excellent melts with a milder profile than Swiss.

Serving Suggestions

Serve these roast beef sandwiches with a side of pickles, coleslaw, or simple potato chips for a classic deli feel. For dipping, try a warm beef consomme or au jus gravy to turn them into a delicious beef dip style sandwich.

A sandwich with meat and cheese on a wooden table. Pin it
A sandwich with meat and cheese on a wooden table. | lanatable.com

Serve immediately while warm and melty. Any leftover sauce can be offered on the side or saved for the next batch.

Frequently Asked Questions About Recipes

→ What type of air fryer works best?

A standard basket air fryer is ideal for this sandwich, fitting two at a time and ensuring even toasting and warming.

→ Can I make an open faced version?

Yes, simply reduce the cook time by about one minute to avoid over-toasting the open sandwich.

→ What alternatives exist for the horseradish sauce?

You can swap horseradish for garlic aioli or mayonnaise to achieve a milder, creamy flavor.

→ How can I replace stone ground mustard?

Dijon mustard works well as a substitute, or you may omit it for a less tangy taste.

→ Is there a suitable dipping option?

Yes, warming some beef consommé or Au Jus gravy makes a perfect dip to enhance the sandwich experience.

→ How should leftovers be stored?

Store in an airtight container for up to 2-3 days; the bread may soften over time.

Air Fryer Roast Beef Sandwich

Tender roast beef and Swiss cheese meld with a tangy sauce for a warm, toasted sandwich made in the air fryer.

Prep Time
10 minutes
Cooking Time
6 minutes
Total Preparation Time
16 minutes
Crafted By: Lana

Type of Recipe: Restaurant Favorites

Recipe Difficulty: Easy

Cuisine Type: American

Number of Servings: 4 Serving Size (4 sandwiches)

Dietary Options: ~

Ingredients You'll Need

→ Sauce

01 ⅓ cup mayonnaise
02 1 tablespoon stone ground mustard
03 3 teaspoons prepared horseradish

→ Sandwich

04 4 brioche buns
05 8 slices Swiss cheese
06 1 pound thinly sliced deli roast beef

Step-by-Step Instructions

Step 01

Combine mayonnaise, stone ground mustard, and prepared horseradish in a small bowl until smooth.

Step 02

Optionally line the air fryer basket with aluminum foil. Place bottom and top brioche buns in the basket and spread the sauce evenly on each bun.

Step 03

Place one slice of Swiss cheese on each bun. On the bottom buns, layer approximately five slices of roast beef each.

Step 04

Cook sandwiches at 370°F (188°C) on the air fryer setting for 4 to 6 minutes until cheese melts, meat is warmed, and buns are lightly toasted. Remove top buns if over-browning occurs during final minutes.

Step 05

Repeat assembly and cooking steps for remaining sandwiches. Use any leftover sauce as a condiment. Serve warm.

Extra Tips & Details

  1. Use a standard basket air fryer for best results and adjust cooking times for different air fryer models.
  2. Open-faced sandwiches can be made by reducing cook time by one minute.
  3. Substitute horseradish with garlic aioli or mayonnaise if preferred.
  4. Dijon mustard can replace stone ground mustard for a milder flavor.
  5. Leftovers keep well in an airtight container for 2 to 3 days but bread may become soggy.

Must-Have Kitchen Tools

  • Basket style air fryer
  • Small mixing bowl
  • Aluminum foil (optional)

Allergen Information

Double-check ingredient labels for potential allergens, and consult an expert if uncertain.
  • Contains dairy and eggs
  • Contains gluten (buns)

Nutritional Information (per portion)

These nutrition stats are for general guidance and aren't a substitute for professional advice.
  • Calories: 761
  • Fat: 48 g
  • Carbohydrates: 40 g
  • Protein: 44 g