Best Beef Enchilada Casserole

Section: Creative Tex-Mex and Fusion Dishes

This beef enchilada casserole blends seasoned ground beef, refried beans, enchilada sauce, and Mexican cheese layered with flour tortillas for a rich and satisfying dish. Ground beef is cooked with onions, green chiles, and taco seasoning before layering with sauce and tortillas. It’s topped with a generous layer of melted cheese and baked until bubbly. Perfect for weeknight dinners, it offers bold, comforting flavors in an easy-to-assemble casserole form. Leftovers store well and reheat easily.

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Crafted By Lana
Updated on Thu, 22 Jan 2026 00:44:40 GMT
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A plate of food with a fork on it. | lanatable.com

This beef enchilada casserole brings all the rich flavors of traditional enchiladas into an easy layered dish that your whole family will love. It’s perfect for busy weeknights when you want something comforting without the fuss of rolling individual enchiladas. This recipe combines seasoned ground beef, creamy refried beans, tangy enchilada sauce, and melty cheese between layers of tender tortillas, making it a satisfying meal that easily feeds a crowd.

I discovered this recipe when I needed a quick Mexicaninspired dinner and now it’s become a goto in my rotation. The flavors meld beautifully, and everyone always asks for seconds.

Ingredients

  • Ground beef: two pounds to provide hearty flavor and protein choose lean if you want to reduce fat
  • Diced white onion: half a cup for sweetness and depth fresh and firm onions work best
  • Can of green chiles: four ounces adds a mild heat and slight smokiness drained before adding
  • Taco seasoning: one ounce packet for authentic Mexican spices pick a quality brand or make your own blend for extra freshness
  • Can of refried beans: sixteen ounces for creaminess and binding the layers creamed style works best for spreading
  • Flour tortillas: two dozen typically medium sized for soft layers choose fresh tortillas without cracks for best texture
  • Enchilada sauce: enough to cover the bottom and layers about two cups brings tangy and rich flavor use your favorite brand or homemade sauce
  • Mexican blend cheese: two cups shredded offers gooey, melty topping mix of cheddar, Monterey Jack, and quesadilla cheese gives a balanced flavor

Instructions

Sauté the Aromatics:
In a large saucepan over medium heat, add the ground beef and diced white onions. Cook, breaking up the beef, until it is browned and the onions are translucent, about eight minutes. Drain excess grease carefully to avoid a greasy casserole base.
Add the Flavor:
Stir in the drained green chiles and taco seasoning. Mix thoroughly so the seasoning coats the beef evenly. Let cook another two minutes to release the spices’ aroma into the meat.
Incorporate the Beans:
Add the refried beans directly to the beef mixture. Stir well until the beans are fully blended and heated through. This adds richness and helps the casserole layers stick together.
Prepare the Tortillas:
Using a sharp knife or pizza cutter, cut the flour tortillas into quarters if desired. This step is optional but helps avoid overlapping layers and provides more even coverage.
Layer the Casserole:
Lightly grease a large casserole dish. Pour a thin layer of enchilada sauce to coat the bottom. Spread one third of the beef and bean mixture over the sauce. Follow with a generous layer of tortilla pieces, then pour more enchilada sauce on top. Repeat the layers two more times, finishing with a layer of shredded cheese on top.
Bake to Perfection:
Preheat your oven to 375 degrees Fahrenheit. Cover the casserole with foil and bake for 20 minutes. Remove the foil and bake another 5 to 10 minutes, or until the cheese is melted and bubbly with some golden spots.
Serve and Garnish:
Once out of the oven, let the casserole rest for five minutes. Serve topped with sour cream, fresh cilantro, diced bell peppers, or any other toppings you love to add fresh flavor and texture.
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A plate of food with a fork. | lanatable.com

I always appreciate the green chiles in this dish because they add a subtle but important kick that brightens the savory beef mixture. One memorable night when I served this at a family gathering, my niece said it tasted like a restaurant special which made me proud of bringing this simple comfort food to the table.

Storage Tips

Keep any leftover casserole tightly covered in an airtight container in the refrigerator where it stays fresh for up to four days. Reheat gently in the microwave or oven until warmed through, taking care not to overcook and dry it out. You can also freeze portions by wrapping them securely with plastic wrap and foil; frozen slices thaw quickly and reheat nicely in the oven.

Ingredient Substitutions

Swapping lean ground turkey or chicken keeps it lighter without sacrificing flavor. Using black beans or pinto beans instead of refried beans is a great option for texture variation and added fiber. Try homemade enchilada sauce for a fresher taste and to control spice levels more precisely.

Serving Suggestions

This casserole pairs well with a fresh green salad for a contrast in texture and brightness. Serve with rice and pickled jalapeños to round out the meal. Add a dollop of guacamole or sliced avocado to complement the cheesy richness and add creaminess.

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A close up of a delicious cheese and meat dish. | lanatable.com

Let the casserole rest a few minutes after baking to set up for cleaner slices. Serve warm with your favorite toppings.

Frequently Asked Questions About Recipes

→ Can I substitute ground beef with another protein?

Yes, ground turkey or shredded chicken can be used as lighter alternatives without sacrificing flavor.

→ What type of cheese works best in this casserole?

A Mexican blend cheese or a mix of Monterey Jack and cheddar melts beautifully and balances the spices well.

→ How should I store leftovers?

Keep leftovers in an airtight container refrigerated for up to 3-4 days for best freshness.

→ Can I prepare the casserole ahead of time?

Yes, you can assemble the layers and refrigerate it before baking. Just add extra bake time if baking from cold.

→ What toppings complement the casserole?

Fresh cilantro, sour cream, diced tomatoes, sliced green onions, and chopped bell peppers add bright, fresh flavors.

→ Is cutting the tortillas necessary?

No, cutting tortillas is optional. Some prefer smaller pieces for less overlap, but whole tortillas work fine.

Best Beef Enchilada Casserole

Hearty layers of seasoned beef, melty cheese, beans, and tortillas baked for a flavorful family meal.

Prep Time
25 minutes
Cooking Time
25 minutes
Total Preparation Time
50 minutes
Crafted By: Lana

Type of Recipe: Tex-Mex & Fusion

Recipe Difficulty: Easy

Cuisine Type: Mexican

Number of Servings: 8 Serving Size

Dietary Options: ~

Ingredients You'll Need

→ Meat and Vegetables

01 2 pounds ground beef
02 1/2 cup diced white onion
03 4-ounce can green chiles

→ Seasonings and Sauces

04 1-ounce package taco seasoning
05 16-ounce can refried beans
06 2 cups enchilada sauce

→ Bases

07 8 flour tortillas, cut into quarters

→ Cheese

08 2 cups shredded Mexican cheese blend

Step-by-Step Instructions

Step 01

Cook the ground beef and diced onions in a large skillet over medium heat until the beef is browned and onions are translucent. Drain excess grease.

Step 02

Stir in the green chiles and taco seasoning, mixing well to combine.

Step 03

Add refried beans to the meat mixture and stir until evenly incorporated.

Step 04

Lightly grease a 9x13-inch casserole dish and spread a thin layer of enchilada sauce evenly on the bottom.

Step 05

Place a layer of quartered tortillas over the enchilada sauce. Spoon some meat mixture on top, then drizzle enchilada sauce over the meat. Repeat layering until all ingredients are used, finishing with a layer of shredded cheese.

Step 06

Preheat the oven to 350°F (175°C). Bake the casserole for 20 to 25 minutes until the cheese is melted and bubbly.

Extra Tips & Details

  1. Cutting the tortillas into quarters is optional but prevents overlapping and ensures even layering.
  2. For a lighter version, substitute ground turkey for beef and black or pinto beans for refried beans.

Must-Have Kitchen Tools

  • Large skillet
  • 9x13-inch casserole dish

Allergen Information

Double-check ingredient labels for potential allergens, and consult an expert if uncertain.
  • Contains gluten and dairy

Nutritional Information (per portion)

These nutrition stats are for general guidance and aren't a substitute for professional advice.
  • Calories: 1070
  • Fat: ~
  • Carbohydrates: ~
  • Protein: ~